Naloxone

Drug CategoryDrugIHD Dosing

Administration Timing Around HD Session

Miscellaneous Medications Naloxone 0.4-2mg IV PRN Anytime During HD

Molecular Weight    (Da)

Excreted Unchanged (%)Normal Half-Life (Hours)ESRD Half-Life (Hours)Plasma Protein Binding (%)Volume of Distribution (L/kg)Dialytic Plasma Clearance (ml/min)% Dialyzed
327.37 N/A 1-1.5 N/A 54 3 N/A N/A

References:

    • Aronoff GR, Bennett WM, Berns JS, Brier ME, Kasbekar N, Mueller BA, et al. Drug Prescribing in Renal Failure. Philadelphia: American College of Physicians;2007.
    • DrugBank [Online]. 2013 Feb 6 [cited 2013 Feb 6]; Available from: URL: http://www.drugbank.ca/drugs/DB01183